However, the level of MPO or ROS production did not predict sensitivity to ASC in AML samples (Figure 4A, 4B, 4C and 4D) as the percentage of ROS-positive cells did not correlate with the percentage of apoptotic cells by ASC (Spearman's correlation 0.32; p = 0.17, Figure 4E). This evidence concerns the gene MPO and acute myeloid leukemia.