Of significance is that A549 cells, an aggressively growing and proliferating lung cancer cell type, was strongly impacted by anti-IL6 antibody treatment, which substantially enhanced the polyI:C-induced apoptosis by increasing caspase 3/7 activity by up to 50% after 24-h treatment compared to isotype controls (Figure 7A). This evidence concerns the gene CASP3 and lung carcinoma.