LAMB2 and lung carcinoma: Treatment with 10 μg/mL polyI:C for 7 days significantly attenuated the three-dimensional growth of A549, NCI-H292 and NCI-H358 by 26%, 44% and 21%, respectively in matrigel, suggesting that polyI:C would presumably elicit a significant impact on suppression of oncogenic transformation of lung cancer cells in the laminin- and collagen- rich basement membrane in vivo.