MKI67 and neoplasm: Moreover, Multivariate Cox proportional survival analysis showed that Ki-67 (P = 0.000) and DBCCR1 expressions (P = 0.000), tumor grade (P = 0.001), tumor metastasis (P = 0.001) and tumor invasion (P = 0.000) were independent prognostic biomarkers of overall survival among the patients (Table 2).