The results showed that the relative MMP-11 levels were positively correlated with the expression of FAK (Spearman rank correlation coefficient r =0.2935, p<0.0001) and Src (Spearman rank correlation coefficient r =0.1817, p<0.0001) mRNAs in HNSCC (Figures 4E-4F). This evidence concerns the gene PTK2 and head and neck squamous cell carcinoma.