Moreover, lncRNA UCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR-216b and activation of FGFR1/ERK signaling pathway [26] and is upregulated in breast cancer [27], colorectal cancer [28], esophageal squamous cell carcinoma [29] and bladder carcinoma [30]. Here, UCA1 is linked to esophageal squamous cell carcinoma.