We also found that some Ngly1−/− embryos showed anemia (12/28 [42.86%], Fig 2E, left panel) or edema (4/28 [14.29%], Fig 2F, left panel), which were not observed in Ngly1+/+ embryos (0/44, Fig 2E and 2F, right panel). The gene discussed is NGLY1; the disease is anemia.