Comparative analysis of the expression profiles among ICC, SMC, and PDGFRα+ cells showed that ICC were indeed enriched in well-known ICC markers (Ano1, Kit, and Prkcq) as well as unknown, new genes (Thbs4, Elovl6, Gja1, Gpr133, Edn3, Hprt, and Etv1) (Fig 3A). The gene discussed is ELOVL6; the disease is intrahepatic cholangiocarcinoma.