Our analysis of the TCGA data for breast cancer [7] revealed upregulation of 26% of the Cu proteome proteins: F5, ATP7B, SLC31A1, SCO2, HEPHL1, CUTA, ATOX1, COX17, TYRP1, MT3, LOX-like proteins 1 and 2, SPARC, and MOXD1. This evidence concerns the gene F5 and breast cancer.