The ROC curves of ATX for predicting early fibrosis (≥F1 vs. controls), significant fibrosis (≥F2), severe fibrosis (≥F3), and cirrhosis (F4) in total, male, and female patients are presented in Fig. 5 and comparisons of AUC between ATX and other fibrosis markers in predicting fibrosis stage are summarized in Table 4. The gene discussed is ENPP2; the disease is Cirrhosis.