Semeraro et al., found that neuroblastoma tumor samples express the NKp30 ligand, B7-H6, and some patients with metastatic neuroblastoma had high levels of soluble B7-H6 in their serum, which was associated with reduced expression of NKp30 on the surface of NK cells and higher degree of metastases (99). Here, NCR3 is linked to neoplasm.