Gonzalez-Sarrias et al. (2016) found relevant changes in cancer markers and identified the induction of p21waf1/Cip1 (CDKN1A) as a common step underlying urolithin anticancer properties. Interestingly, miR-224 down-regulation or miR-215 up-regulation was associated with CDKN1A induction (Gonzalez-Sarrias et al., 2016). Here, CDKN1A is linked to cancer.