Within the 39 upregulated pathways pool, increased transcript levels of enzymes (UDP-glucuronosyltransferases, uridine phosphorylase, glutathione S-transferases, dihydropyrimidine dehydrogenases, and xanthine dehydrogenase) involved in xenobiotic (drug) biodegradation and metabolism were induced by MdSGHV infection. The gene discussed is HPGDS; the disease is infection.