BRAF and neoplasm: Other factors associated with worse OS were an age of <50 years (HR 1.4, 95% CI 1.1-1.8; p=0.006), right-sided tumor origin (HR 1.5, 95% CI 1.0-2.1; p=0.031), poor differentiation (HR 1.5, 95% CI 1.2-2.0; p=0.001), KRAS mutations (HR 1.5, 95% CI 1.1-1.9; p=0.004), and BRAF mutations (HR 1.7, 95% CI 1.1-2.7; p=0.015) (Table 3, Figure 3).