HDAC1 and metastatic malignant neoplasm in the lymph nodes: However, the groups positive and negative for lymph node metastasis (OR = 1.49, 95% CI = 0.85–2.61, P = 0.16) (Figure 6), as well as distant metastasis (OR = 1.67, 95% CI = 0.91–3.08, P = 0.10) (Figure 7), did not show a significant difference in HDAC1 expression in the gastrointestinal cancer patients overall.