CSN2 and hepatocellular carcinoma: As shown in (Figure 7D), the nuclear localization of p65 (12 of 15 cases) and CSN2 (13 of 15 cases) in HCC tumor tissues (T) (red arrow) was higher than their para-tumor tissues (PT), which is highly consistent with the enhanced expression of RMP in these tissues (Figure 7D and 7E).