Meanwhile, the pooled data of eligible studies also indicated that high UCA1 expression was significant correlated with poor grade cancer (pooled OR = 2.74, 95% CI 2.04–3.70, p < 0.001, I2 = 49.5%, pH = 0.1) and positive lymph node metastasis (pooled OR = 2.43, 95% CI 1.72–3.41, p < 0.001). Here, UCA1 is linked to cancer.