Apart from these core PC pathways, we also observed enrichment of several other important pathways that are related to cancer such as p53 signaling, VEGF signaling, phosphatidylinositol signaling, EbrB signaling, Jak-STAT signaling, Fc gamma R-mediated phagocytosis, insulin signaling, cytokine-cytokine receptor interaction, chemokine signaling pathway, natural killer cell mediated cytotoxicity, T cell receptor signaling pathway and B cell receptor signaling pathway. The gene discussed is INS; the disease is cancer.