The networks are associated with groups of classical oncogenes that play a pivotal role in the tumorigenic process in glioma such as PTEN, P53, ERK1/2, JNK, VEGF and caspase 1 (Figures 6E, 6F, Supplementary Figures 10A-10E) [41–43]. The gene discussed is MAPK3; the disease is glioma.