As shown in Supplementary Table 3, the analysis revealed enrichment of 45 KEGG categories and 714 GO categories (P-values < 0.05 after FDR adjustment), demonstrating the predicted miRNA targets are involved in many important pathways associated with cancer development, including adherent junction, Wnt, TGF-beta, VEGFR and MAPK signaling pathways (Table 5). Here, KDR is linked to cancer.