PIK3CA and breast cancer: In the recessive model, BC patients carrying PIK3CA rs2699887 GA/AA genotypes had a significantly longer DFS (median survival time, MST=89 months, 95% CI=73-106 months) and OS time (MST=106 months, 95% CI=80-132 months) in comparison to the carriers who had AA genotype (DFS:MST=40 months, 95% CI=30-51 months, OS: MST=52 months, 95% CI=42-62 months), as shown in Figure 2A, 2B.