These prognostic factors include age [29–31], tumor stage [31], tumor grade [32–34], tumor size [30, 33, 35, 36], nodal status [30, 33, 36], hormone receptor status [32, 34, 35, 37], gene mutations [38], tumor marker status [39], drug exposure and chemotherapy [30, 40, 41]. The gene discussed is NR4A1; the disease is neoplasm.