In this study, the DNMT3A mRNA levels in 56 NSCLC tissue samples with different rs1550117 A>G genotypes were also tested, and DNMT3A was significantly upregulated in GA samples (1.6-fold) and AA samples (3.1-fold) than in GG samples (Figure 1B). This evidence concerns the gene DNMT3A and non-small cell lung carcinoma.