Consistent with reparixin pharmacological effects, p-FAK activation in breast cancer cells was previously reported to be implicated in anchorage-independent growth [55] and in breast cancer tumorigenesis and progression [56–60] whereas in sensory neurons β1-integrin activity and FAK phosphorylation at tyrosine 397 (FAKpY397) are linked to neuronal polarization as well as neurite outgrowth and branching [61]. Here, PTK2 is linked to breast carcinoma.