Intriguingly, tumor markers were also found to be elevated finally in case B2 [CA125: 81.07 U/ml (normal range: 0–35)], case B3 [CEA: 5.85 ng/ml (normal range: 0–5); CA125: 179.14 U/ml (normal range: 0–35)] and case B4 [CEA: 20.85 ng/ml (normal range: 0–5); CA125: 50.07 U/ml( normal range: 0–35)], and all decreased to normal level after EGFR-tyrosine kinase inhibitor treatment. Here, EGFR is linked to neoplasm.