We found that connections through TnTs could be established between cells of the same (CK+-cell-to-CK+-cell, VIM+-cell-to-VIM+-cell or CK+VIM+-cell-to-CK+VIM+-cell) or different phenotypes (CK+-cell-to-VIM+-cell, or CK+-cell-to-CK+VIM+-cell), (Figure 2B) thus indicating that TnTs are not a specific feature of an epithelial or mesenchyme cancer cell phenotype. The gene discussed is VIM; the disease is cancer.