In line with above findings for primary cancer cells, we also found that miR-25-93-106b KO mice bear 50% more CD274+ myeloid CD11b+ BM cells as compared to WT mice (Figure 7A & Supplementary Figure 7A/7B) and the increase is even further enhanced upon TBI (which reduces expression of miR-25-93-106b). The gene discussed is CD274; the disease is cancer.