The survival analysis revealed that in lung adenocarcinoma patients, the ones with high expression of GBE1 and HK2 represented shorter overall survival than those with low expression of GBE1 (P=0.0332) and HK2 (P=0.0246), evidence supporting an association between these genes and cancer survival (Figure 4). This evidence concerns the gene GBE1 and lung adenocarcinoma.