Although previous studies have demonstrated that EMT-TFs played a fundamental role in the initiation, aggregation, progression, and metastasis of BC by inducing the activation of NOTCH1, TP53, and TGF-β cascade [10, 13, 33], EMT-TFs’ expression patterns, in comparison to miR-34a, have not been well characterized in human BC. The gene discussed is TP53; the disease is breast cancer.