Mesenchymal recurrent bladder cancer cells secreted multiple cytokines and growth factors, including transforming growth factor beta, interleukin-8, EGF, Wnt, and granulocyte-macrophage colony-stimulating factor, many of which are involved in malignancy progression in various types of carcinomas [16–18]. Here, CXCL8 is linked to urinary bladder carcinoma.