TNFSF8 and cancer: Upregulated genes included members of the tumor necrosis factor superfamily (TNFRSF9, TNFRSF11B, and TNFSF8), ABC transporters (ABCB1 and ABCG2), and nuclear factor (NF)-κB-related genes (NFKB2 and RELB), all of which induce stemness in cancer cells [24, 26–27].