Additionally, media from AML-12 cells stably expressing HA-URI and treated with bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide (BPTES), a selective inhibitor of glutaminase GLS1 reducing α-ketoglutarate levels, decreased BMOL cell numbers (Figures 7D and 7E) (Xiang et al., 2015). This evidence concerns the gene GLS and acute myeloid leukemia.