Participants with T2DM had elevated weight (p = 0.0031), BMI (p = 0.001), FBG (<0.0001), Insulin (p = 0.0088), intact PTH (p = 0.0349), HOMA-IR (p< 0.0001), TG (p = 0.0113), LDL-c (0.0184), TC (p = 0.1967) and BAI (p = 0.0046) and wider WC (p = 0.0004) and HC (p = 0.0012) with corresponding decrease HDL-C (p = 0.0008), 25(OH)D (p< 0.0001), HOMA- β (p< 0.0001) compared to non-T2DM participants. This evidence concerns the gene INS and type 2 diabetes mellitus.