The IHC analysis on the biopsies from123 GC patients showed that KIAA1199 protein expression had no significant effect on such clinical parameters regarding age, sex, vascular invasion and differentiation, but was correlated with depth of invasion, lymph node status (N-staging), metastasis and TNM staging (T-staging: P<0.01; N-staging: P<0.01; M-staging: P<0.05; TNM: P<0.01), which was mostly consistent with the KIAA1199 mRNA expression clinical characteristics analysis in GC patients (Table 2). The gene discussed is CEMIP; the disease is gastric cancer.