KLK3 and posterior cortical atrophy: However, in patients with PSA 4–10 ng/ml, although the improvement in AUC was similar, the result was not statistically significant in predicting PCa (0.863 vs. 0.803, p = 0.125) (Supplementary Figure 3B) or significant PCa (0.899 vs. 0.846, p = 0.176) (Supplementary Figure 3D).