DNMT3B and acute myeloid leukemia: But in a research of acute myeloid leukemia, Niederwieser C et al. [116] found that high DNMT3B expression seemingly an independent prognostic factor from mechanisms of DNA hypermethylation and/or microRNA-dependent gene repression, at the same time they attempted to explain why the miR-133b presented unique upregulation in high DNMT3B expressers.