STK31 and pachyonychia congenita: Next, we evaluated STK31 expression in PC specimens through bioinformatics analysis of RNA sequencing (RNA-seq) of The Cancer Genome Atlas (TCGA) PAAD data (178 PC samples), which indicated that STK31 was elevated in about 85% of patients with PC (Figure 1C), which was also supported by the HPA (Figure 1E).