MYC and pancreatic ductal adenocarcinoma: Recently, patient-derived xenograft models of pancreatic ductal adenocarcinoma (PDAC) showed that JQ1, an inhibitor of CT genes in the bromodomain and extraterminal (BET) protein family (BRDT), suppresses PDAC development by inhibiting both MYC (v-myc avian myelocytomatosis viral oncogene homolog) activity and inflammatory signals [11].