HOXA9 and acute myeloid leukemia: GSEA using SE-associated signatures [4] and curated gene sets (C2 v.5.1) from MSigDB confirmed high enrichment of genes associated with hematopoietic stem cells (NES 3.4) and NUP98-HOXA9-target genes (NES 2.9) in responder cells, relative to non-responders AML cells (Figure 8C and Supplementary Table 6).