Broad profiling of SEL120-34A and Senexin B in a panel of AML cell lines revealed several sensitive (GI50<1 μM)- responder cell lines (SKNO-1, KG-1, HEL-60, MOLM-16, MV-4-11, OciAML-2, MOLM-6 and OciAML-3), consistent with the effective inhibition range of STAT1 S727 and STAT5 S726 (Figure 7C). This evidence concerns the gene STAT1 and acute myeloid leukemia.