Total 14 (12%)Rash, n = 4 (3%)Increased ALT, n = 2 (2%)Increased bilirubin, n = 2 (2%)Rhabdomyolysis, n = 2 (2%)≤1%: Increased AST, liver disorder, colitis, autoimmune colitis, diarrhea, hypothyroidism, arthralgia, maculopapular rash, arthritis, rheumatoid arthritis, muscle spasms, tenosynovitis. The gene discussed is GPT; the disease is arthritic joint disease.