NR3C1 and acute leukemia: In a more recent cohort studying acute leukemia transplant patients (181), three polymorphisms, presence of toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) (alternatively named MAL) allele T (rs8177374) in the patient, absence of the glucocorticoid receptor (GCR) haplotype (consisting of rs6198, rs33389, and rs33388) ACT in the patient and absence of HSPA1L (or HSP70-hom) +2437 (rs2227956) allele C in the patient were associated with decreased survival.