INS and infection: Additionally, these results provide further evidence of what Olive and Sassetti (52) describe as a pathogen’s ability to “sense the metabolic environment of the host, adapting to changing nutrient availability.” Further, these phosphorylation alterations at the gut level during the first 3 weeks after infection of day-old broilers with ST appear to lead to key metabolic changes that affected fatty acid and glucose metabolism through the 5′-AMPK and the insulin/mTOR signaling pathway in the skeletal muscle were altered (53).