JAM2 and cancer: When compared to control PNA, we observed consistent decreased expression of IL-6 and MMP-9 and increased JAM2, HOXD13 and IKBA expression in the majority of ovarian (Fig. 2C, Supplementary Fig. S4A,B) and breast (Fig. 2D, Supplementary Fig. S4C,D) cancer cell lines examined (some genes omitted from graphs due to very high threshold cycle (CT) values or no detectable expression in some cell lines examined).