LATS1 and hepatocellular carcinoma: The expression of LATS1 was significantly downregulated in the tumor tissues compared with the adjacent tissues (P < 0.001) (Fig. 6a, Additional file 5: Figure S7A), and the Kaplan–Meier analysis indicated that the lower LATS1 expression was related to poor overall survival in patients with HCC (P = 0.032).