TGFB1 and polyostotic fibrous dysplasia: Also, PFD inhibits the up-regulation of fibrosis-related factors such as COL1A1and IL-6 induced by TGF-β1 and BLM along with indicators of oxidative stress such as ROS and MDA level induced by BLM, alleviates the inflammatory infiltration and pathological damage of pulmonary fibrosis, while only PFD treatment for wild-type mice do not display these effects.