Other actions of melatonin that are likely related to the capacity of melatonin to hinder mitotic activity of mammary cancer cells includes its ability to arrest the cell cycle in the G1 phase [206], to curb aromatase activity [207], to keep in check aerobic glycolysis (Warburg effect) and to restrain the uptake of the n-6 fat, linoleic acid (LA), a growth factor for breast cancer cells [208]. The gene discussed is CYP19A1; the disease is breast cancer.