LPS, in turn, induces insulin resistance through the activation of the transcription factor NF-κB (nuclear factor kappa-beta) which promotes the expression of inflammatory cytokines [4], such as tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6), which contribute to the impairment of insulin signaling, affecting kidney function [11]. This evidence concerns the gene IL1B and Insulin resistance.