IL1B and metabolic dysfunction-associated steatohepatitis: Alternative M2 macrophages sustain insulin sensitivity via the secretion of anti-inflammatory cytokines such as IL-4 and IL-13, while classical M1 macrophages secrete pro-inflammatory cytokines such as TNF-α, IL-6, and IL-1β, which, in turn, leads to insulin resistance and NASH [18,19].