CD4 and HIV infectious disease: We found that patients with the highest level of immunosuppression (ie, those with a CD4+ T-cell count of <150) had a significantly higher median CSF neutrophil percentage (25%) than patients with a CD4+ T-cell count of ≥150 cells/μL (10%; P = .021) and patients without HIV infection (5%; P < .0001); patients with the highest level of immunosuppression also had significantly greater cytokine concentrations than patients in the other 2 groups (Supplementary Figure 2A).