We next analyzed the effects of the four SNPs in the CYP1A2 and CYP3A4 genes on a series of clinicopathological parameters in the patient cohort, including age at diagnosis and menstrual status, clinic stage, tumor size, histological grade, LNM and the status of ER, PR, HER2, Ki67 and P53. The gene discussed is PGR; the disease is neoplasm.