AFP and hepatocellular carcinoma: In the haplotype analysis, the GT haplotype was associated with an increased risk for AFP cut-off levels of 200 and 400 ng/ml in HBV-related HCC (GT vs. AC; adjusted P=0.004, adjusted OR= 1.629, 95% CI= 1.164–2.281 for an AFP cut-off level of 200 ng/ml; and adjusted P= 0.006, adjusted OR= 1.592, 95% CI= 1.140–2.224 for an AFP cut-off level of 400 ng/ml).