Based on our previous finding that TGF-β1-related miRNAs contribute to tumor progression [8, 9, 24], we explored TGF-β1 inhibited miRNAs in colorectal cancer cells, including miR-4313, miR-3691-3p, miR-196a-3p, miR-324-3p, and miR-4723-3p, and demonstrated that only miR-196a-3p was restrained in breast cancer lines. The gene discussed is TGFB1; the disease is breast cancer.